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Behavior Modification
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Efficacy of Cognitive-Behavioral Therapy for Comorbid Panic Disorder With Agoraphobia and Generalized Anxiety Disorder

Joane Labrecque, PhD

Université du Québec à Montréal Hôpital Louis-H. Lafontaine, Montréal, joane.labrecque{at}internet.uqam.ca

André Marchand, PhD

Université du Québec à Montréal Hôpital Louis-H. Lafontaine, Montréal

Michel J. Dugas, PhD

Concordia University, Montréal Hôpital du Sacré-Cœur, Montréal

Andrée Letarte, MPs

Hôpital Louis-H. Lafontaine, Montréal

The goal of this study was to evaluate the efficacy of cognitive-behavioral therapy for comorbid panic disorder with agoraphobia (PDA) and generalized anxiety disorder (GAD) by combining treatment strategies for both disorders. A single-case, multiple-baseline design across participants was used. Three participants with primary PDA and secondary GAD took part in the study. The efficacy of the treatment was assessed by means of a structured interview, self-administered questionnaires, and daily self-monitoring measures. After treatment, 2 of the 3 participants achieved high end-state functioning and maintained this level of functioning at 3-, 6-, and 12-month follow-ups. The third participant also improved but only reached high end-state functioning at 6-month follow-up. It therefore appears that the combined treatment is relatively effective for PDA–GAD comorbidity. Possible avenues for improving the treatment are suggested.

Key Words: comorbidity • anxiety • cognitive-behavioral therapy • panic disorder with agoraphobia • generalized anxiety disorder

Behavior Modification, Vol. 31, No. 5, 616-637 (2007)
DOI: 10.1177/0145445507301132
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