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Behavior Modification
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A Review of Behavioral Treatments used for Lesch-Nyhan Syndrome

Lynn Olson

University of South Carolina

Daniel Houlihan

Mankato State Universityhouly{at}vax1.mankato.msus.edu.

Lesch-Nyhan syndrome is a genetic disorder resulting in hyperuricemia, choreoathetosis, mental retardation, and self-mutilation. The most salient feature of this disorder is the self-injurious behavior (SIB). Although the utility of behavioral interventions with SIB has been well documented, behavioral interventions with Lesch-Nyhan syndrome have been limited in number and long-term success. This article reviews the behavioral treatments that have been used in treating individuals with Lesch-Nyhan syndrome and discusses the strengths and weaknesses of these methods. Suggestions for future directions in the use of behavioral interventions for controlling SIB in Lesch-Nyhan syndrome are provided.

Behavior Modification, Vol. 24, No. 2, 202-222 (2000)
DOI: 10.1177/0145445500242003
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 Behav ModifHome page
A. E. Bergen, S. W. Holborn, and V. C. Scott-Huyghebaert
Functional Analysis of Self-Injurious Behavior in an Adult with Lesch-Nyhan Syndrome
Behav Modif, April 1, 2002; 26(2): 187 - 204.
[Abstract] [PDF]